Rule #1: Sign up with a staffing agency. Find out what agencies the school you want to work at utilizes and sign up with them. This was the key component of getting the great position that I have. The agency will help you tweak your resume, etc. Working with them really serves as a pre-interview. MIT is looking for people who know their stuff. Make sure you have some background in Academia and emphasize your ability to work cross-departmentally. Eventually everyone works together so you have to be a team player.